MRI-based comparative study of different mild cognitive impairment subtypes: protocol for an observational case-control study.

ABSTRACT:

Introduction

Amnestic mild cognitive impairment (aMCI) and vascular mild cognitive impairment (VaMCI) comprise the 2 main types of mild cognitive impairment (MCI). The first condition generally progresses to Alzheimer's disease, whereas the second is likely to develop into vascular dementia (VD). The brain structure and function of patients with MCI differ from those of normal elderly individuals. However, whether brain structures or functions differ between these 2 MCI subtypes has not been studied. This study is designed to analyse neuroimages of brain in patients with VaMCI and aMCI using multimodality MRI (structural MRI (sMRI), functional MRI and diffusion tensor imaging (DTI)).

Methods and analysis

In this study, 80 participants diagnosed with aMCI, 80 participants dia

SUBMITTER: Yu Y 

PROVIDER: S-EPMC5353263 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature