Ontology highlight
ABSTRACT: Background
Obese Latino adolescents are disproportionately impacted by insulin resistance and type 2 diabetes. Prediabetes is an intermediate stage in the pathogenesis of type 2 diabetes and represents a critical opportunity for intervention. However, to date, no diabetes prevention studies have been conducted in obese Latino youth with prediabetes, a highly vulnerable and underserved group. Therefore, we propose a randomized-controlled trial to test the short-term (6-month) and long-term (12-month) efficacy of a culturally-grounded, lifestyle intervention, as compared to usual care, for improving glucose tolerance and reducing diabetes risk in 120 obese Latino adolescents with prediabetes.Methods
Participants will be randomized to a lifestyle intervention or usual care gro
SUBMITTER: Soltero EG
PROVIDER: S-EPMC5353870 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature