Survival outcomes and surgical intervention of small intestinal neuroendocrine tumors: a population based retrospective study.

ABSTRACT:

Background

Small intestinal neuroendocrine tumors (SiNETs) without distant metastasis typically behave in an indolent manner, but there can be heterogeneity. We aimed to define the survival outcomes and impacts of surgical intervention.

Methods

A retrospective cohort study was conducted by using data from the Surveillance, Epidemiology, and End Results (SEER) database. Clinicopathologic features were analyzed in 4407 patients between 2000 and 2012. The cancer specific survival (CSS) was calculated by the Kaplan-Meier method. Multivariable Cox regression models with hazard ratios (HRs) were constructed to analyze survival outcomes and risk factors.

Results

The adjusted incidence of early SiNETs is 1.3/100,000. Tumors are most commonly located in the ileum and are small

SUBMITTER: Wu L 

PROVIDER: S-EPMC5354882 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature