Biochemical and molecular modulation of CCl₄-induced peripheral and central damage by Tilia americana var. mexicanaextracts.

ABSTRACT: Around the world, species from the genus Tilia are commonly used because of their peripheral and central medicinal effects; they are prepared as teas and used as tranquilizing, anticonvulsant, and analgesic agents. In this study, we provide evidence of the protective effects of organic and aqueous extracts (100 mg/kg, i.p.) obtained from the leaves of Tilia americana var. mexicana on CCl₄-induced liver and brain damage in the rat. Protection was observed in the liver and brain (cerebellum, cortex and cerebral hemispheres) by measuring the activity of antioxidant enzymes and levels of malondialdehyde (MDA) using spectrophotometric methods. Biochemical parameters were also assessed in serum samples from the CCl₄-treated rats. The T. americana

SUBMITTER: Coballase-Urrutia E 

PROVIDER: S-EPMC5357111 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature