Serum uric acid levels in patients with Parkinson's disease: A meta-analysis.

ABSTRACT:

Background

Lower serum uric acid (UA) levels have been reported as a risk factor in Parkinson's disease (PD). However, the results have been inconsistent so far.

Objectives

The aim of the present study was to clarify the potential relationship of uric acid with PD.

Methods

Comprehensive electronic search in pubmed, web of science, and the Cochrane Library database to find original articles about the association between PD and serum uric acid levels published before Dec 2015. Literature quality assessment was performed with the Newcastle-Ottawa Scale. Random-effects model was used to estimate the standardized mean differences (SMDs) with 95% confidence intervals (CIs). Heterogeneity across studies was assessed using I2 and H2 statistics. Sensitivity analyses to assess

SUBMITTER: Wen M 

PROVIDER: S-EPMC5358777 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature