Investigation of inhomogeneous and anisotropic material behavior of porcine thoracic aorta using nano-indentation tests.

ABSTRACT: This study investigates the inhomogeneity and anisotropy of porcine descending thoracic aorta in three dimensions using a custom-made nano-indentation technique and a quasi-linear viscoelastic modeling approach. The indentation tests were conducted in axial, circumferential, and radial orientations with about 100 μm spatial resolution. The ratio of the elastic moduli obtained in different orientations was used to quantify the tissue local anisotropy. The distal sections were generally stiffer than the proximal ones in both axial and circumferential indentations. Four distinct layers were identified across the thickness with significantly different mechanical properties. The stiffness of the medial quadrant was significantly lower than all other quadrants in axial indentation. The anisotrop

SUBMITTER: Kermani G 

PROVIDER: S-EPMC5359050 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature