Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction.

ABSTRACT:

Background

Elevated homocysteine (Hc) levels have a well-established and clear causal relationship to epithelial damage leading to coronary artery disease. Furthermore, it is strongly associated with other metabolic syndrome variables, such as hypertension, which is correlated with type II diabetes mellitus (T2DM). Studies on T2DM in relation to Hc levels have shown both positive and negative associations. The aim of the present study is to examine the relationship between Hc levels and risk of T2DM in the Lebanese population.

Methods

We sought to identify whether Hc associates positively or negatively with diabetes in a case-control study, where 2755 subjects enrolled from patients who had been catheterized for coronary artery diagnosis and treatment. We further sought to i

SUBMITTER: Platt DE 

PROVIDER: S-EPMC5359933 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature