Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study.

ABSTRACT:

Background

Potentially modifiable lifestyle factors may influence cognitive health in later life and offer potential to reduce the risk of cognitive decline and dementia. The concept of cognitive reserve has been proposed as a mechanism to explain individual differences in rates of cognitive decline, but its potential role as a mediating pathway has seldom been explored using data from large epidemiological studies. We explored the mediating effect of cognitive reserve on the cross-sectional association between lifestyle factors and cognitive function in later life using data from a population-based cohort of healthy older people.

Methods and findings

We analysed data from 2,315 cognitively healthy participants aged 65 y and over in the Cognitive Function and Ageing Study Wa

SUBMITTER: Clare L 

PROVIDER: S-EPMC5360216 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature