nab-Paclitaxel for the treatment of breast cancer: an update across treatment settings.

ABSTRACT:

Purpose

The purpose of this systematic review is to discuss recent studies and ongoing trials of nab-paclitaxel in breast cancer and to examine the potential role of nab-paclitaxel as a backbone for immuno-oncology therapies.

Methods

PubMed and selected congress proceedings were searched for studies of nab-paclitaxel in breast cancer published between 2013 and 2015. All phase II and III clinical trials, retrospective analyses, and institutional studies were included. Active, ongoing, phase II or III trials on nab-paclitaxel that were listed on ClinicalTrials.gov were also included.

Results

Sixty-three studies, including 23 in early-stage and 30 in metastatic breast cancer (some studies not classifiable by setting), were included in this ana

SUBMITTER: Brufsky A 

PROVIDER: S-EPMC5361712 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature