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A directional 103Pd brachytherapy device: Dosimetric characterization and practical aspects for clinical use.


ABSTRACT:

Purpose

A brachytherapy (BT) device has been developed with shielding to provide directional BT for preferentially irradiating malignancies while sparing healthy tissues. The CivaSheet is a flexible low-dose-rate BT device containing CivaDots with 103Pd shielded by a thin Au disk. This is the first report of a clinical dosimetric characterization of the CivaSheet device.

Methods and materials

Radiation dose distributions near a CivaDot were estimated using the MCNP6 radiation transport code. CivaSheet arrays were also modeled to evaluate the dose superposition principle for treatment planning. The resultant data were commissioned in a treatment planning system (TPS) (VariSeed 9.0), and the accuracy of the dose superposition principle was evaluated for summing indi

SUBMITTER: Rivard MJ 

PROVIDER: S-EPMC5362288 | biostudies-literature | 2017 Mar - Apr

REPOSITORIES: biostudies-literature