Disclosing Genetic Risk for Coronary Heart Disease: Attitudes Toward Personal Information in Health Records.

ABSTRACT:

Introduction

Incorporating genetic risk information in electronic health records (EHRs) will facilitate implementation of genomic medicine in clinical practice. However, little is known about patients' attitudes toward incorporation of genetic risk information as a component of personal health information in EHRs. This study investigated whether disclosure of a genetic risk score (GRS) for coronary heart disease influences attitudes toward incorporation of personal health information including genetic risk in EHRs.

Methods

Participants aged 45-65 years with intermediate 10-year coronary heart disease risk were randomized to receive a conventional risk score (CRS) alone or with a GRS from a genetic counselor, followed by shared decision making with a physician using the same

SUBMITTER: Brown SA 

PROVIDER: S-EPMC5362329 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature