Relationship between LINC00341 expression and cancer prognosis.

ABSTRACT: LINC00341 is a novel long intergenic non-protein coding RNA with unknown functions. In our report, we investigated LINC00341 expression and its prognostic value in cancer patients. DNA over-methylation triggered low expression of LINC00341 and that was associated with poor prognosis in cancers. A meta-analysis further confirmed that high expression of LINC00341 was associated with a better prognosis in cancer patients. Both gene set enrichment analysis and meta-analysis showed that LINC00341 inhibited cancer metastasis. Finally, a large-scale multicentre analysis supported a prognostic value of LINC00341 in cancers.

SUBMITTER: Liao M 

PROVIDER: S-EPMC5362486 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature