A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease.

ABSTRACT:

Rationale

Chronic obstructive pulmonary disease (COPD) is often unrecognized and untreated.

Objectives

To develop a method for identifying undiagnosed COPD requiring treatment with currently available therapies (FEV₁ <60% predicted and/or exacerbation risk).

Methods

We conducted a multisite, cross-sectional, case-control study in U.S. pulmonary and primary care clinics that recruited subjects from primary care settings. Cases were patients with COPD and at least one exacerbation in the past year or FEV₁ less than 60% of predicted without exacerbation in the past year. Control subjects were persons with no COPD or with mild COPD (FEV₁ ≥60% predicted, no exacerbation in the past year). In random forests analyses, we identified the smalle

SUBMITTER: Martinez FJ 

PROVIDER: S-EPMC5363964 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature