Prevalence of ST1193 clone and IncI1/ST16 plasmid in E-coli isolates carrying bla_CTX-M-55 gene from urinary tract infections patients in China.

ABSTRACT: To study molecular epidemiology of CTX-M-55-carrying Escherichia coli isolates from urinary tract infections (UTIs) in China. 111 bla_CTX-M-55-positive E.coli isolates from UTIs patients in China were studied. Pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) were used to analyze the homologies among the strains. Conjugation experiments, S1nuclease PFGE and PCR analysis were performed to characterize plasmids harboring bla_CTX-M-55 and their genetic environment. 111 isolates were clustered into 86 individual pulsotypes and three clusters by PFGE. Fifty-five (49.5%) of the isolates belonged to 8 STs. Most of the ST1193 isolates belonged to one PFGE cluster. Transconjugants (n = 45) derived from randomly selected bla_CTX-M-55 donors (

SUBMITTER: Xia L 

PROVIDER: S-EPMC5364490 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature