Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes.

ABSTRACT: The regio- and diastereoselective zirconocene-catalyzed carbomagnesiation of cyclobutenes is herein reported to afford configurationally stable cyclobutylmagnesium species that could subsequently react with a large variety of electrophiles to give polysubstituted cyclobutane species as a single diastereoisomer.

SUBMITTER: Roy SR 

PROVIDER: S-EPMC5365058 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature