Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding.

ABSTRACT: To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.

SUBMITTER: Wang B 

PROVIDER: S-EPMC5365087 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature