Persistence of weight loss and acquired behaviors 2 y after stopping a 2-y calorie restriction intervention.

ABSTRACT: Background: Calorie restriction (CR) influences aging processes and extends average and maximal life spans. The CALERIE 2 (Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy Phase 2) study was the first randomized clinical trial to examine the metabolic and psychological effects of CR in nonobese humans.Objective: We conducted a 2-y follow-up study of adults who underwent 2 y of CR or ad libitum (control) consumption and determined whether weight loss and acquired behaviors persisted after the study ended when participants determined their own lifestyle behaviors.Design: In this prospective, longitudinal study, we assessed differences in weight, body composition, psychological function, and energy expenditure in 39 nonobese [body mass index (in

SUBMITTER: Marlatt KL 

PROVIDER: S-EPMC5366052 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature