Association of Fat Mass and Obesity-associated Gene Variant with Lifestyle Factors and Body Fat in Indian Children.

ABSTRACT:

Context

Common intronic variants of the fat mass and obesity-associated (FTO) gene have been associated with obesity-related traits in humans.

Aims

(1) The aim of this study is to study the distribution of FTO gene variants across different body mass index (BMI) categories and (2) to explore the association between FTO gene variants and lifestyle factors in obese and normal weight Indian children.

Subjects and methods

Fifty-six children (26 boys, mean age 10.3 ± 2.2 years) were studied. Height, weight, and waist and hip circumference were measured. Physical activity (questionnaire) and food intake (food frequency questionnaire) were assessed. Body fat percentage (%BF) was measured by dual-energy X-ray absorptiometry. FTO allelic variants at rs9939609 site were detecte

SUBMITTER: Parthasarthy LS 

PROVIDER: S-EPMC5367234 | biostudies-literature | 2017 Mar-Apr

REPOSITORIES: biostudies-literature