Ontology highlight
ABSTRACT:
SUBMITTER: Papagiannakopoulos T
PROVIDER: S-EPMC5367626 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Cell metabolism 20160728 2
Circadian rhythms are 24-hr oscillations that control a variety of biological processes in living systems, including two hallmarks of cancer, cell division and metabolism. Circadian rhythm disruption by shift work is associated with greater risk for cancer development and poor prognosis, suggesting a putative tumor-suppressive role for circadian rhythm homeostasis. Using a genetically engineered mouse model of lung adenocarcinoma, we have characterized the effects of circadian rhythm disruption ...[more]