Toxinotyping and Sequencing of Clostridium difficile Isolates from Patients in a Tertiary Care Hospital of Northern India.

ABSTRACT:

Background

Clostridium difficile is an important cause of infectious colitis among hospitalized patients across the globe. The pathogenic potential of C. difficile in producing significant morbidity and mortality is mainly due to production of toxins A and B. The outbreaks of C. difficile infection (CDI) are due to changes in the genetic sequences of the organism. There is hardly any molecular study reported on the prevalent types of C. difficile strains in India. Toxinotyping and sequencing of locally circulating C. difficile isolates from patients presenting to our tertiary care center of North India were done.

Materials and methods

C. difficile strains (n = 174) isolated from 1,110 fecal samples from patients

SUBMITTER: Singh M 

PROVIDER: S-EPMC5368245 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature