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A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells.

ABSTRACT: A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO₃^-/SO₃^2-). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO₃^- in liver cancer cells rather than normal liver cells, implying the diagnosal potential of the probe.

SUBMITTER: Li DP

PROVIDER: S-EPMC5368602 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells.

Li Dong-Peng DP Wang Zhao-Yang ZY Cui Jie J Wang Xin X Miao Jun-Ying JY Zhao Bao-Xiang BX

Scientific reports 20170328

A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO3-/SO32-). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO3</su ...[more]

PMID: 28349998

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