Prenatal folic acid and risk of asthma in children: a systematic review and meta-analysis.

ABSTRACT:

Background

Childhood asthma has become a critical public health problem because of its high morbidity and increasing prevalence. The impact of nutrition and other exposures during pregnancy on long-term health and development of children has been of increasing interest.

Objective

We performed a systematic review and meta-analysis of the association of folate and folic acid intake during pregnancy and risk of asthma and other allergic outcomes in children.

Design

We performed a systematic search of 8 electronic databases for articles that examined the association between prenatal folate or folic acid exposure and risk of asthma and other allergic outcomes (eg, allergy, eczema, and atopic dermatitis) in childhood. We performed a meta-analysis by using a random-effects m

SUBMITTER: Crider KS 

PROVIDER: S-EPMC5369603 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature