Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study.

ABSTRACT:

Background

Patients with bronchiectasis often have concurrent comorbidities, but the nature, prevalence, and impact of these comorbidities on disease severity and outcome are poorly understood. We aimed to investigate comorbidities in patients with bronchiectasis and establish their prognostic value on disease severity and mortality rate.

Methods

An international multicentre cohort analysis of outpatients with bronchiectasis from four European centres followed up for 5 years was done for score derivation. Eligible patients were those with bronchiectasis confirmed by high-resolution CT and a compatible clinical history. Comorbidity diagnoses were based on standardised definitions and were obtained from full review of paper and electronic medical records, prescriptions, and in

SUBMITTER: McDonnell MJ 

PROVIDER: S-EPMC5369638 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature