Dissociation between skin test reactivity and anti-aeroallergen IgE: Determinants among urban Brazilian children.

ABSTRACT:

Background

The dissociation between specific IgE and skin prick test reactivity to aeroallergens, a common finding in populations living in low and middle-income countries, has important implications for the diagnosis and treatment of allergic diseases. Few studies have investigated the determinants of this dissociation. In the present study, we explored potential factors explaining this dissociation in children living in an urban area of Northeast Brazil, focusing in particular on factors associated with poor hygiene.

Methods

Of 1445 children from low income communities, investigated for risk factors of allergies, we studied 481 with specific IgE antibodies to any of Blomia tropicalis, Dermatophagoides pteronyssinus, Periplaneta americana and Blatella germanica allergens. D

SUBMITTER: Alcantara-Neves NM 

PROVIDER: S-EPMC5369757 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature