Rituximab maintenance therapy for patients with diffuse large B-cell lymphoma: A meta-analysis.

ABSTRACT:

Purpose

The addition of rituximab to standard chemotherapy has significantly improved survival in patients with lymphoma. Recently, maintenance therapy with rituximab has been shown to prevent relapse and provide survival benefits for patients with follicular or mantle cell lymphoma. However, the effects of rituximab in patients with diffuse large B-cell lymphoma (DLBCL) remain unclear. Two new studies involving rituximab in the treatment of DLBCL were performed this past year. We performed a meta analysis to evaluate the effects of rituximab maintenance treatment of patients with DLBCL.

Methods

Several databases (PubMed, MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials) databases were reviewed for relevant randomized controlled trials published prior to M

SUBMITTER: Zhou X 

PROVIDER: S-EPMC5371376 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature