Measurement of exhaled nitric oxide concentration in patients with obstructive sleep apnea: A meta-analysis.

ABSTRACT:

Background

Exhaled nitric oxide (eNO) has been proposed as a noninvasive measure of airway inflammation. However, its value in patients with obstructive sleep apnea (OSA) is still controversial. The authors aim to assess the difference in eNO levels between patients with OSA and controls by a meta-analysis.

Methods

A systematic search was performed in the PubMed, EMBASE, the Cochrane Library, and MEDLINE databases to collect relevant studies published from 1996 to 2016. Eligible studies that reported eNO levels in patients with OSA were included. STATA (version 12.0) was used for data analysis.

Results

Two hundred eighty-four studies were reviewed for inclusion, with 16 studies pooled for analysis (16 studies for fractional exhaled nitric oxide [FENO], 5 for alveolar

SUBMITTER: Zhang D 

PROVIDER: S-EPMC5371487 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature