Core-genome scaffold comparison reveals the prevalence that inversion events are associated with pairs of inverted repeats.

ABSTRACT:

Background

Genome rearrangement describes gross changes of chromosomal regions, plays an important role in evolutionary biology and has profound impacts on phenotype in organisms ranging from microbes to humans. With more and more complete genomes accomplished, lots of genomic comparisons have been conducted in order to find genome rearrangements and the mechanisms which underlie the rearrangement events. In our opinion, genomic comparison of different individuals/strains within the same species (pan-genome) is more helpful to reveal the mechanisms for genome rearrangements since genomes of the same species are much closer to each other.

Results

We study the mechanism for inversion events via core-genome scaffold comparison of different strains within the same species. We fo

SUBMITTER: Wang D 

PROVIDER: S-EPMC5372343 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature