Episodic Memory Retrieval Benefits from a Less Modular Brain Network Organization.

ABSTRACT: Most complex cognitive tasks require the coordinated interplay of multiple brain networks, but the act of retrieving an episodic memory may place especially heavy demands for communication between the frontoparietal control network (FPCN) and the default mode network (DMN), two networks that do not strongly interact with one another in many task contexts. We applied graph theoretical analysis to task-related fMRI functional connectivity data from 20 human participants and found that global brain modularity-a measure of network segregation-is markedly reduced during episodic memory retrieval relative to closely matched analogical reasoning and visuospatial perception tasks. Individual differences in modularity were correlated with memory task performance, such that lower modularity levels w

SUBMITTER: Westphal AJ 

PROVIDER: S-EPMC5373132 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature