Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea.

ABSTRACT: Cyanobacteria are major sources of oxygen, nitrogen, and carbon in nature. In addition to the importance of their primary metabolism, some cyanobacteria are prolific producers of unique and bioactive secondary metabolites. Chemical investigations of the cyanobacterial genus Moorea have resulted in the isolation of over 190 compounds in the last two decades. However, preliminary genomic analysis has suggested that genome-guided approaches can enable the discovery of novel compounds from even well-studied Moorea strains, highlighting the importance of obtaining complete genomes. We report a complete genome of a filamentous tropical marine cyanobacterium, Moorea producens PAL, which reveals that about one-fifth of its genome is devoted to production of secondary metabolit

SUBMITTER: Leao T 

PROVIDER: S-EPMC5373345 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature