The Potential Cost-Effectiveness of HIV Vaccines: A Systematic Review.

ABSTRACT:

Objective

The aim of this paper was to review and compare HIV vaccine cost-effectiveness analyses and describe the effects of uncertainty in model, methodology, and parameterization.

Methods

We systematically searched MEDLINE (1985 through May 2016), EMBASE, the Tufts CEA Registry, and reference lists of articles following Cochrane guidelines and PRISMA reporting. Eligibility criteria included peer-reviewed manuscripts with economic models estimating cost-effectiveness of preventative HIV vaccines. Two reviewers independently assessed study quality and extracted data on model assumptions, characteristics, input parameters, and outcomes.

Results

The search yielded 71 studies, of which 11 met criteria for inclusion. Populations included low-income (n=7), middle-income (

SUBMITTER: Adamson B 

PROVIDER: S-EPMC5373805 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature