The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans.

ABSTRACT: One of the drawbacks during second-generation biofuel production from plant lignocellulosic biomass is the accumulation of glucose, the preferred carbon source of microorganisms, which causes the repression of hydrolytic enzyme secretion by industrially relevant filamentous fungi. Glucose sensing, subsequent transport and cellular signalling pathways have been barely elucidated in these organisms. This study therefore characterized the transcriptional response of the filamentous fungus Aspergillus nidulans to the presence of high and low glucose concentrations under continuous chemostat cultivation with the aim to identify novel factors involved in glucose sensing and signalling. Several transcription factor- and transporter-encoding genes were identified as being differentially regulated,

SUBMITTER: Dos Reis TF 

PROVIDER: S-EPMC5374493 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature