Relationship Between Central Retinal Vessel Trunk Location and Visual Field Loss in Glaucoma.

ABSTRACT:

Purpose

To study the relationship between horizontal central retinal vessel trunk location (CRVTL) on glaucomatous optic discs and sector-specific visual field (VF) loss.

Design

Retrospective cross-sectional study.

Methods

CRVTL of 421 eyes from 421 patients was manually tracked on the horizontal optic disc axis on fundus images. Focal circumpapillary retinal nerve fiber layer thickness (cpRNFLT) measurements were extracted from optical coherence tomography (OCT). The relationship between focal visual field (VF) loss and CRVTL and focal cpRNFLT was studied by linear regression models. Furthermore, we related central VF loss to CRVTL and focal cpRNFLT separately for mild (VF mean deviation [MD] ≥-6 dB), moderate (-12 dB ≤ MD <-6 dB), and severe (MD <-12 dB) glaucoma.

SUBMITTER: Wang M 

PROVIDER: S-EPMC5376509 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature