Residential Pesticide Exposures in Pregnancy and the Risk of Sporadic Retinoblastoma: A Report From the Children's Oncology Group.

ABSTRACT:

Purpose

To examine whether parental pesticide exposure contributes to the development of sporadic retinoblastoma.

Design

Case-control study.

Methods

Data were collected by a large multicenter study of sporadic retinoblastoma in which parents of 99 unilateral and 56 bilateral age-matched case-control pairs were interviewed by telephone. Retrospective exposure information was collected on the type, location, timing, and frequency of residential pesticide use. We used conditional logistic regression analyses to estimate odds ratios for maternal pesticide exposure in the month before or during pregnancy and to assess whether the type of product, and the circumstances under which it was applied, were associated with risk of disease.

Results

Unilateral retinoblastoma

SUBMITTER: Omidakhsh N 

PROVIDER: S-EPMC5376525 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature