Detecting Change Using Standard Global Perimetric Indices in Glaucoma.

ABSTRACT:

Purpose

Various global indices are available to summarize results from standard automated perimetry. This study asks which index can detect significant deterioration earliest, for a fixed specificity.

Design

Comparison of prognostic indices.

Methods

Two cohorts were tested. A test-retest cohort contained 5 reliable visual fields, within a short interval, from 45 eyes of 23 participants with glaucoma and/or likelihood of developing glaucoma. A separate longitudinal cohort contained 508 eyes from 330 participants, tested on average 13 times. Three global indices were extracted: mean deviation (MD), pattern standard deviation (PSD), and visual field index (VFI). For each index we defined a critical P value Crit_Index, such that 5% of test-retest series showed s

SUBMITTER: Gardiner SK 

PROVIDER: S-EPMC5376527 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature