Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation.

ABSTRACT: The circadian clock regulates physiological processes central to growth and survival. To date, most plant circadian clock studies have relied on diurnal transcriptome changes to elucidate molecular connections between the circadian clock and observable phenotypes in wild-type plants. Here, we have integrated RNA-sequencing and protein mass spectrometry data to comparatively analyse the lhycca1, prr7prr9, gi and toc1 circadian clock mutant rosette at the end of day and end of night. Each mutant affects specific sets of genes and proteins, suggesting that the circadian clock regulation is modular. Furthermore, each circadian clock mutant maintains its own dynamically fluctuating transcriptome and proteome profile specific to subcellular compartments. Most of the m

SUBMITTER: Graf A 

PROVIDER: S-EPMC5376707 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature