Ru-Catalyzed Estragole Isomerization under Homogeneous and Ionic Liquid Biphasic Conditions.

ABSTRACT: The isomerization of estragole to trans-anethole is an important reaction and is industrially performed using an excess of NaOH or KOH in ethanol at high temperatures with very low selectivity. Simple Ru-based transition-metal complexes, under homogeneous, ionic liquid (IL)-supported (biphasic) and "solventless" conditions, can be used for this reaction. The selectivity of this reaction is more sensitive to the solvent/support used than the ligands associated with the metal catalyst. Thus, under the optimized reaction conditions, 100% conversion can be achieved in the estragole isomerization, using as little as 4 × 10^-3 mol % (40 ppm) of [RuHCl(CO)(PPh₃)₃] in toluene, reflecting a total turnover number (TON) of 25 000 and turnover frequencies (TOFs)

SUBMITTER: Leal BC 

PROVIDER: S-EPMC5377274 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature