Quantitative evaluation of statistical errors in small-angle X-ray scattering measurements.

ABSTRACT: A new model is proposed for the measurement errors incurred in typical small-angle X-ray scattering (SAXS) experiments, which takes into account the setup geometry and physics of the measurement process. The model accurately captures the experimentally determined errors from a large range of synchrotron and in-house anode-based measurements. Its most general formulation gives for the variance of the buffer-subtracted SAXS intensity σ²(q) = [I(q) + const.]/(kq), where I(q) is the scattering intensity as a function of the momentum transfer q; k and const. are fitting parameters that are characteristic of the experimental setup. The model gives a concrete procedure for calculating realistic measurement errors for simulated SAX

SUBMITTER: Sedlak SM 

PROVIDER: S-EPMC5377352 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature