Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men.

ABSTRACT:

Background

Adequate muscle fibre perfusion is critical for the maintenance of muscle mass; it is essential in the rapid delivery of oxygen, nutrients and growth factors to the muscle, stimulating muscle fibre growth. Muscle fibre capillarization is known to decrease substantially with advancing age. However, whether (relative) low muscle fibre capillarization negatively impacts the muscle hypertrophic response following resistance exercise training in older adults is unknown.

Methods

Twenty-two healthy older men (71 ± 1 years) performed 24 weeks of progressive resistance type exercise training. To assess the change in muscle fibre characteristics, percutaneous biopsies from the vastus lateralis muscle were taken before and following 12 and 24 weeks of the intervention progra

SUBMITTER: Snijders T 

PROVIDER: S-EPMC5377411 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature