Quantifying Fundus Autofluorescence in Patients With Retinitis Pigmentosa.

ABSTRACT:

Purpose

Using quantitative fundus autofluorescence (qAF), we analyzed short-wavelength autofluorescent (SW-AF) rings in RP.

Methods

Short-wavelength autofluorescent images (486 nm excitation) of 40 patients with RP (69 eyes) were acquired with a confocal scanning laser ophthalmoscope equipped with an internal fluorescent reference. Mean qAF was measured in eight preset segments (qAF8) and in region of interest (ROI)-qAF (200-700 μm) within and external to the borders of the rings at superior, temporal, and inferior sites relative to the ring. For both groups, qAF in patients with RP was compared to age-similar and race/ethnicity-matched healthy eyes at equivalent retinal locations.

Results

In 71% of eyes of RP patients, qAF8 acquired internal to the inner border of th

SUBMITTER: Schuerch K 

PROVIDER: S-EPMC5377994 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature