Drug interactions between hormonal contraceptives and antiretrovirals.

ABSTRACT:

Objective

To summarize published evidence on drug interactions between hormonal contraceptives and antiretrovirals.

Design

Systematic review of the published literature.

Methods

We searched PubMed, POPLINE, and EMBASE for peer-reviewed publications of studies (in any language) from inception to 21 September 2015. We included studies of women using hormonal contraceptives and antiretrovirals concurrently. Outcomes of interest were effectiveness of either therapy, toxicity, or pharmacokinetics. We used standard abstraction forms to summarize and assess strengths and weaknesses.

Results

Fifty reports from 46 studies were included. Most antiretrovirals whether used for therapy or prevention, have limited interactions with hormonal contraceptive methods, with the ex

SUBMITTER: Nanda K 

PROVIDER: S-EPMC5378006 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature