Distinct roles of light-activated channels TRP and TRPL in photoreceptors of Periplaneta americana.

ABSTRACT: Electrophysiological studies in Drosophila melanogaster and Periplaneta americana have found that the receptor current in their microvillar photoreceptors is generated by two light-activated cationic channels, TRP (transient receptor potential) and TRPL (TRP-like), each having distinct properties. However, the relative contribution of the two channel types to sensory information coding by photoreceptors remains unclear. We recently showed that, in contrast to the diurnal Drosophila in which TRP is the principal phototransduction channel, photoreceptors of the nocturnal P. americana strongly depend on TRPL. Here, we perform a functional analysis, using patch-clamp and intracellular recordings, of P. americana photoreceptors after RNA interference to knock

SUBMITTER: Saari P 

PROVIDER: S-EPMC5379922 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature