Personality and addictive behaviours in early Parkinson's disease and REM sleep behaviour disorder.

ABSTRACT:

Introduction

Changes in personality have been described in Parkinson's disease (PD), with suggestion that those with established disease tend to be risk averse with a disinclination for addictive behaviour. However, little is known about the earliest and prodromal stages. Personality and its relationship with addictive behaviours can help answer important questions about the mechanisms underlying PD and addiction.

Methods

941 population-ascertained PD subjects within 3.5 years of diagnosis, 128 patients with rapid eye movement sleep behaviour disorder (RBD) and 292 control subjects were fully characterised for motor symptoms, non-motor symptoms and across the following 5 personality domains: 1) neuroticism 2) extraversion 3) conscientiousness 4) agreeableness 5) openness usi

SUBMITTER: Baig F 

PROVIDER: S-EPMC5380654 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature