Acid/base triggered interconversion of μ-η²:η²-peroxido and bis(μ-oxido) dicopper intermediates capped by proton-responsive ligands.

ABSTRACT: CuII2(μ-η²:η²-peroxido) and CuIII2(μ-oxido)₂ cores represent key intermediates in copper/dioxygen chemistry, and they are mechanistically important for biological hydroxylation and oxidation reactions mediated by dinuclear (type III) copper metalloenzymes. While the exact nature of the active species in different enzymes is still under debate, shifting equilibria between Cu _x /O₂ species is increasingly recognized as a means of switching between distinct reactivity patterns of these intermediates. Herein we report comprehensive spectroscopic, crystallographic and computational analysis of a family of synthetic CuII2(μ-η²:η²-peroxido) and CuIII2(μ-oxido)₂ dicopper complexes with a bis(oxazoline) (

SUBMITTER: Goswami VE 

PROVIDER: S-EPMC5380878 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature