Evolutionary gradient of predicted nuclear localization signals (NLS)-bearing proteins in genomes of family Planctomycetaceae.

ABSTRACT:

Background

The nuclear envelope is considered a key classification marker that distinguishes prokaryotes from eukaryotes. However, this marker does not apply to the family Planctomycetaceae, which has intracellular spaces divided by lipidic intracytoplasmic membranes (ICMs). Nuclear localization signal (NLS), a short stretch of amino acid sequence, destines to transport proteins from cytoplasm into nucleus, and is also associated with the development of nuclear envelope. We attempted to investigate the NLS motifs in Planctomycetaceae genomes to demonstrate the potential molecular transition in the development of intracellular membrane system.

Results

In this study, we identified NLS-like motifs that have the same amino acid compositions as experimentally identified NLSs in g

SUBMITTER: Guo M 

PROVIDER: S-EPMC5381049 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature