US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry.

ABSTRACT:

Background

In the US familial hypercholesterolemia (FH), patients are underidentified, despite an estimated prevalence of 1:200 to 1:500. Criteria to identify FH patients include Simon Broome, Dutch Lipid Clinic Network (DLCN), or Make Early Diagnosis to Prevent Early Deaths (MEDPED). The use of these criteria in US clinical practices remains unclear.

Objective

To characterize the FH diagnostic criteria applied by US lipid specialists participating in the FH Foundation's CASCADE FH (CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia) patient registry.

Methods

We performed an observational, cross-sectional analysis of diagnostic criteria chosen for each adult patient, both overall and by baseline patient characteristics, at 15 clinical sites

SUBMITTER: Ahmad ZS 

PROVIDER: S-EPMC5381273 | biostudies-literature | 2016 Sep-Oct

REPOSITORIES: biostudies-literature