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Evolution and Diversity of Transposable Elements in Vertebrate Genomes.


ABSTRACT: Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via transposition or retrotransposition and often make up large fractions of vertebrate genomes. Here, we review the current understanding of vertebrate TE diversity and evolution in the context of recent advances in genome sequencing and assembly techniques. TEs make up 4-60% of assembled vertebrate genomes, and deeply branching lineages such as ray-finned fishes and amphibians generally exhibit a higher TE diversity than the more recent radiations of birds and mammals. Furthermore, the list of taxa with exceptional TE landscapes is growing. We emphasize that the current bottleneck in genome analyses lies in the proper annotation of TEs and provide examples where superficial analyses led to misleading conclu

SUBMITTER: Sotero-Caio CG 

PROVIDER: S-EPMC5381603 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature