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Molecular Evolution of piggyBac Superfamily: From Selfishness to Domestication.


ABSTRACT: The piggyBac transposable element was originally isolated from the cabbage looper moth, Trichoplusia ni, in the 1980s. Despite its early discovery and specificity compared to the other Class II elements, the diversity and evolution of this superfamily have been only partially analyzed. Two main types of elements can be distinguished: the piggyBac-like elements (PBLE) with terminal inverted repeats, untranslated region, and an open reading frame encoding a transposase, and the piggyBac-derived sequences (PGBD), containing a sequence derived from a piggyBac transposase, and which correspond to domesticated elements. To define the distribution, their structural diversity and phylogenetic relationships, analyses were conducted using known PBLE and PGBD sequences to scan databases. From this da

SUBMITTER: Bouallegue M 

PROVIDER: S-EPMC5381638 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature