Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study.

ABSTRACT:

Background

Occupational pesticide use is associated with lung cancer in some, but not all, epidemiologic studies. In the Agricultural Health Study (AHS), we previously reported positive associations between several pesticides and lung cancer incidence.

Objective

We evaluated use of 43 pesticides and 654 lung cancer cases after 10 years of additional follow-up in the AHS, a prospective cohort study comprising 57,310 pesticide applicators from Iowa and North Carolina.

Methods

Information about lifetime pesticide use and other factors was ascertained at enrollment (1993-1997) and updated with a follow-up questionnaire (1999-2005). Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking (smoking

SUBMITTER: Bonner MR 

PROVIDER: S-EPMC5381995 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature