The Vivax Surveyor: Online mapping database for Plasmodium vivax clinical trials.

ABSTRACT:

Introduction

Recurrent P. vivax infections are associated with significant morbidity and mortality. Although radical cure can reduce recurrent infection, it is confounded by antimalarial resistance and the lack of safe and effective hypnozoitocidal treatment. This study documents the available literature of published clinical trials of P. vivax, providing an up to date, online, open access tool to view and download available information.

Methods

A systematic review was conducted according to PRISMA guidelines to identify prospective P. vivax therapeutic clinical trials with at least 28 days follow-up published between 1st January 1960 and 12th October 2016. Treatment arms and evidence of chloroquine resistance were mapped to trial sites.

Results

Since 1960, a total of

SUBMITTER: Commons RJ 

PROVIDER: S-EPMC5382033 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature