Neural responses to negative outcomes predict success in community-based substance use treatment.

ABSTRACT:

Background and aims

Patterns of brain activation have demonstrated promise as prognostic indicators in substance dependent individuals (SDIs) but have not yet been explored in SDIs typical of community-based treatment settings.

Design

Prospective clinical outcome design, evaluating baseline functional magnetic resonance imaging data from the Balloon Analogue Risk Task (BART) as a predictor of 3-month substance use treatment outcomes.

Setting

Community-based substance use programs in Bloomington, Indiana, USA.

Participants

Twenty-three SDIs (17 male, aged 18-43 years) in an intensive outpatient or residential treatment program; abstinent 1-4 weeks at baseline.

Measurements

Event-related brain response, BART performance and self-report scores at treatment

SUBMITTER: Forster SE 

PROVIDER: S-EPMC5382058 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature